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We annotated the cell type for a recent human liver cell 10x genomics dataset15 with the integrated data as reference. Sankey diagram revealed that major cell types were correctly predicted, including hepatocytes, endothelial cells and Kupffer cells (specialized macrophages located in the liver). Furthermore, each cell type could be further classified into more precise labels based on datasets uncovering novel sub cell types. A Training set Pre-process by calculating the mean gene expression form the original expression matrix.
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