The ResMed AirSense 11 was designed as the successor to the long-running AirSense 10, but the two machines differ in several meaningful ways beyond just appearance. Here’s a clear, side-by-side breakdown to help you understand what’s actually changed.
Interface and Design
The AirSense 10 uses a button-based control system with a simple, familiar layout. The AirSense 11 replaces this with a full touchscreen display, along with a more compact, lighter housing that’s easier to fit on a nightstand or pack for travel.
Pressure Algorithm and Comfort Settings
Both machines rely on ResMed’s trusted AutoSet algorithm for auto-adjusting pressure, but the resmed airsense 11 autoset includes several refinements not found on the AirSense 10:
- Built-in AutoSet for Her mode – available as a selectable setting on every AutoSet 11 unit, whereas the AirSense 10 required purchasing a separate “For Her” model
- Auto Ramp – automatically detects sleep onset and gradually increases pressure; not available on the AirSense 10
- Adjustable comfort response – choose between soft and standard pressure ramp-up styles, offering more personalization than the AirSense 10’s fixed ramp settings
Onboarding and Support Tools
The AirSense 11 introduces Care Check-In prompts and a Personal Therapy Assistant to help new users adjust to therapy during the first few weeks — tools that simply don’t exist on the AirSense 10.
Accessories and Compatibility
This is one of the most practical differences for anyone considering an upgrade: most AirSense 10 accessories, including humidifier chambers, power supplies, and certain tubing connectors, are not cross-compatible with the AirSense 11. Upgrading typically means purchasing a new ResMed AirSense 11 AutoSet heated humidifier and other accessories rather than reusing your existing ones.
Noise Levels
Both machines are considered very quiet by CPAP standards, and the difference in actual noise output between the two is minor. If reducing machine noise was your main reason for considering an upgrade, the AirSense 11 won’t offer a dramatic improvement in this specific area.
App Connectivity
Both the AirSense 10 and AirSense 11 connect to the myAir app for tracking therapy data, so this isn’t a differentiating factor between the two generations.
Side-by-Side Summary
| Feature | AirSense 10 | AirSense 11 |
|---|---|---|
| Interface | Button-based | Touchscreen |
| AutoSet for Her | Separate model required | Built into every AutoSet unit |
| Auto Ramp | Not available | Available |
| Guided onboarding tools | Not available | Care Check-In, Personal Therapy Assistant |
| Size and weight | Slightly larger and heavier | More compact and lighter |
| Accessory compatibility | N/A | Mostly requires new accessories |
| Noise level | Very quiet | Very quiet (similar) |
| App connectivity | myAir | myAir |
Which One Should You Choose?
If you already own a well-functioning AirSense 10 with stable pressure settings, there’s no urgent need to upgrade — it remains a dependable machine. If you’re a new CPAP user, want the AutoSet for Her mode without buying a separate device, or prefer a more modern touchscreen interface with guided onboarding support, the AirSense 11 is the stronger choice.
Where to Buy
You can view the current AirSense 11 lineup and pricing here:
👉 Shop the ResMed AirSense 11 – CPAPMedTrade
Both machines deliver reliable, effective CPAP therapy — the AirSense 11 simply adds a more modern interface, extra comfort settings, and onboarding tools on top of the same trusted AutoSet foundation.
